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Similarly, misfolded proteins that cause ER stress can elicit the unfolded protein response (UPR) and promote ROS accumulation [5]

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I would check out, it came out a while ago, but I would check out Mark Sisson's book, Primal Endurance, because that is all about like being in a fat burning state on, that's like a low carb diet, but like a similar thing where you are, you're creating a metabolic state in your body that supports fat burning from the dietary choices that you're making