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In these studies, the authors determined that the induction of long-term depression (LTD) is enhanced by blocking Glu uptake that then activates extrasynaptically located N -methyl d-aspartate receptor subtype 2B (NR2B/GRIN2B) receptors, whereas the de-potentiation phenomenon requires activation of N -methyl d-aspartate receptor subtype 2A (NR2A/GRIN2A) receptors

Within this broader effort, lipin-1 provides a useful model for understanding how lipid metabolic nodes coordinate macrophage inflammatory and pro-resolving functions

96, 864868 10.1111/j.1572-0241.2001.03635.x [DOI] [PubMed] [Google Scholar] 92.Kim W.-Y., Jo E.-J., Eom J.S.et al

In certain embodiments this process can be carried out multiple times every few weeks