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DADS and DATS inhibited the expression of adhesion molecules, E-selectin and vascular cell adhesion molecule-1 (VCAM-1), on endothelial cell surface by reversing oxidized LDL-induced inhibition of PI3K/Akt and cAMP responsive element binding protein (CREB) signaling pathways (50)

While these approaches can be effective, they often provide temporary relief and may come with side effects or risks

Increased expression of extracellular glutathione peroxidase in mice with dextran sodium sulfate-induced experimental colitis

Additionally, the decreased rate of GSH efflux from the liver suggested in this study may enhance EtOH-mediated damage to other organ systems