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25 Furthermore, many patients with POTS have associated generalized symptoms including fatigue, malaise, sleep disruption, headache and gastrointestinal symptoms, features often observed in chronic autoimmune disease

ALDH2*2 overexpressing mice are precise models of late-onset (sporadic) Alzheimers disease, while ALDH2 / mice are precise models of early-onset (familiar) Alzheimers disease