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Patients administered DOX can develop acute or chronic side effects, including arrhythmias, pericarditis, ventricular dysfunction, and congestive heart failure 3,4,5

5-(3,4-Dihydroxyphenyl)--valerolactone and its sulphate conjugates, representative circulating metabolites of flavan-3-ols, exhibit anti-adhesive activity against uropathogenic Escherichia coli in bladder epithelial cells