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Nutrients (2022) 14(15):3096

In vitro studies have demonstrated that TNF- can directly suppress sperm motility by 40%60% ( Furthermore, sperm motility is highly dependent on energy derived from glucose metabolism

This suggests that the tumor cells make and store this DSIP-like substance before releasing it

Future research should focus on optimizing the bioavailability of AS-IV in oral formulations, elucidating its mechanisms of action within multi-drug combination therapies, and evaluating its clinical efficacy across varied pathological conditions