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For illustration, it is challenging for cell models to replicate the intact BRB, a highly specialized structure composed of RPE cells, RCECs, and tight junctions, which restricts the entry of Fe + and limits the infiltration of pro-oxidative factors (95)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Santini D., Vincenzi B., Dicuonzo G., Avvisati G., Massacesi C., Battistoni F., Gavasci M., Rocci L., Tirindelli M.C., Altomare V., et al