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The MMA levels, along with decreases in Mmut expression in several organs (Extended Data Fig

In Pratt VM, McLeod HL, Rubinstein WS, Scott SA, Dean LC, Kattman BL, et al

In solvent -80C, 2 years , -20C, 1 year Publications Citing Use of MedChemExpress (MCE) CD38 inhibitor 1 More Signal Transduct Target Ther

In a phase 1 study, Voxelotor (Oxbryta/GBT440) binds specifically to the N-terminus of the alpha subunit of HbS to stabilize the oxygenated hemoglobin state (Strader et al., 2019), thus reducing the predisposition to sickling