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Cardiac arrhythmias also seem to be caused by COVID-19 vaccination [276] (which, of course, includes spike protein or RNA coding for it), and spike protein is known to cause microclots [43,44]

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As such, due to the multifaceted nature of chronic wound pathogenesis and susceptibility to abnormalities in ROS balance, interest in the role of ROS in wound healing, as well as the potential applicability of targeting ROS therapeutically, has grown significantly in recent years 14

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