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Description

Dissection of complex protein dynamics in human thioredoxin

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The successful development of the first highly selective SQOR inhibitors demonstrates that SQOR is indeed a druggable target, opening a new paradigm for treating diseases like heart failure ( in vivo monitoring methods for H 2 S and its metabolites to stratify patients and monitor treatment responses before advancing SQOR-targeted therapies

Calculating the overall loading value: We determine the number of weeks per digit by multiplying the percentage loss of use per digit by the maximum allowable weeks per digit