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Lancet Haematology, 4(11), e524-e533

Vitamin B12 deficiency anemia is most common in people with ancestral history in Northern Europe

Conclusion: Severe comorbidity burden is common in MeVO patients and linked to poorer prognosis when compared to patients without comorbidities

We will also discuss how adrenal exhaustion may be linked to methylation dysfunction associated with MTHFR polymorphisms and how these can be treated through supplementation