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BDNF, brain-derived neurotrophic factor, is the central signaling molecule in neuronal survival, synaptic plasticity, and neurogenesis

IV administration is common in clinical settings for antioxidant therapy

In a convenience sample of deceased NFL football players who donated their brains for research, 110 of 111 had neuropathological evidence of CTE, suggesting that CTE may be related to playing football [note that participation in the brain-donation program was likely motivated by players and their families awareness of links between head trauma and CTE

Additionally, many participants experience increased energy levels and a reduction in cravings, making it easier to adhere to the diet and achieve lasting results