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In response to these safety concerns, the U.S

doi:10.1016/j.jbbm.2007.05.009

Due to its exceptional water-binding capacity, Hyaluronic Acid has become one of the most researched compounds for improving skin moisture, elasticity, and overall appearance while supporting the extracellular matrix

However, some important concerns need to be considered prior to the use of SeNPs in clinical translational applications, such as the safety profile, pharmacokinetics and pharmacodynamics, and specificity and sensitivity in the biological milieu