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Abstract Insulin resistance (IR) is a core pathological feature of type 2 diabetes mellitus (T2DM) and is closely associated with mitochondrial dysfunction in insulin-sensitive tissues, including skeletal muscle, liver, and adipose tissue

Macrophages were washed once in pre-warmed PBS and cultured at 37 C in RPMI-1640 containing 10% FBS, and then infected with suspended Salmonella in serum-free, antibiotic-free medium for 30 min