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Compounded drugs are not FDA-approved and carry no manufacturer accountability or validated dosing protocol

It's largely anecdotal, based on the logical (but not necessarily scientifically validated) idea that putting the peptide closer to the site of injury will make it work better or faster

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Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat