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4 Transfection of cells with mRNA

Tang L, Yu F, Tang B, Yang Z, Fan W, Zhang M, et al

For instance, upregulation of the SSP is driven by the AMP-activated protein kinasemTORC1 axis, leading to elevated S-adenosylmethionine (SAM) production and increased expression of DNA methyltransferases, thereby promoting oncogenic transformation of primary pancreatic ductal epithelial cells ( In hepatocellular carcinoma (HCC), USP10 activates liver kinase B1 (LKB1) through deubiquitination