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Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone

This not only revives the midface area but also softens the look of under-eye hollows and nasolabial folds, giving you a smoother, firmer, and rejuvenated appearance

The weight loss as percentage of the initial weight was -9.3%, -10.5% and -1.8% in the three respective groups