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Introduction Over the past few decades we have witnessed an increase in male reproductive disorders such as cryptorchidism and hypospadias in new-born boys, or infertility and testis cancers in young men ( With respect to male reproductive disorders, chemical substances with anti-androgenic properties such as many phthalates and pesticides are of particular concern ( Another morphometric biomarker of fetal androgen action is areola/nipple retention, in this review simply referred to as nipple retention (NR)

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