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Our findings indicate that GSH depletion within 24 hours after DEM administration was not detrimental for mucosal function as revealed by the lack of evidence of mucosal damage

Evidence also indicated a direct association between phases of migraine attacks and calcitonin gene-related peptide (CGRP), mitochondrial disorders, monoaminergic pathway, magnesium deficiency, and higher serum levels of glutamate (13, 14)

(iii) the branched-chain -ketoacid dehydrogenase complex that is involved in the decarboxylation of ketoacids in the catabolic pathway of the branched-chain amino acids, namely leucine, isoleucine, and valine

One of the first clinical studies of erdosteine, the EQUALIFE study was a randomized placebo-controlled trial of 124 patients with COPD assigned to receive either placebo or 300 mg BID erdosteine for 8 months