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TBK1-mediated DRP1 targeting confers nucleic acid sensing to reprogram mitochondrial dynamics and physiology

In brief, chemical standard libraries of 149 metabolites in seven pooled libraries were prepared and serially diluted in high-performance liquid chromatography (HPLC)-grade water from in a dilution series from 5 mM to 1 M to generate external standard pools, which are used for calibration of isotopically labelled internal standards and to quantify concentrations of metabolites for which internal standards were not available

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Furthermore, by ensuring that the protein is fully digested in the upper GI tract, these enzymes may help prevent undigested proteins from fermenting in the lower gut, thereby reducing the bloating, gas, and discomfort often associated with protein supplementation