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67 In line with a role of ATII in endothelial dysfunction and hypertension, numerous studies have now demonstrated that the therapy with angiotensin-converting enzyme inhibitors and AT-1 receptor blockers is associated with an improvements in endothelial responsiveness 68, 69, 70, 71, 72 (the existence of negative reports also needs to be acknowledged)

Peptides serve as signaling molecules in the body, acting as hormones, neurotransmitters, immune messengers, and regulators of tissue repair

Vukojevi J, Milavi M, Perovi D, et al

However, its therapeutic effects exhibit considerable heterogeneity, and its safety profile and overall applicability require further validation