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The frequency of HLA-B27 is reportedly higher among patients with PsA

The therapeutic scope of probiotics extends to metabolic health, with oral supplementation of Bifidobacterium breve improving glycemic control in T2DM and Anaerobutyricum soehngenii enhancing intestinal barrier function through SCFA production, improving metabolic indicators in prediabetes ( F.n decolonization, and enhances tryptophan metabolism and secondary bile acid conversion, leading to reduced lipid accumulation, decreased inflammatory reaction, and enhanced tumor inhibition effect, providing a promising approach for treating F.n -positive CRC (Zhou et al., 2025)

The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments

Rhamnetin also enhances the efficacy of standard chemotherapeutic agents, such as 5-fluorouracil (5-FU), by inhibiting drug-resistance pathways like PI3K/AKT/mTOR