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Osteopontin, acting both as a cytokine and matricellular protein, decreases TAM cytotoxicity against neoplastic cells and interacts with integrins to activate Wnt-catenin, sustaining iCCA growth and metastasis 97

It is widely used in laboratory, pharmaceutical, and formulation research as a diluent for the reconstitution and dilution of injectable-grade compounds under controlled experimental conditions

They utilized acrylic acid, magnesium hydroxide, and ethylenediamine, followed by the conjugation of CDs with Cholrin e6

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