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In the OlympiA study, one year of olaparib adjuvant therapy after completion of local therapy and (neo)adjuvant chemotherapy significantly improved the 3-year iDFS and DDFS compared to placebo

Representative Masson's trichrome-stained histopathological sections of human corpora cavernosa: non-ED control, physiological Hcy, and hyperhomocysteinemia related ED

In the cytoplasm, amino acids, such as arginine and leucine, can lead to the activation of the GATOR2 complex, which further enhances the binding capacity of Rag GTPases and mTORC1 by inhibiting the hydrolysis of the GATOR1 complex by Rag GTPases 65,66

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