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They're not exact, and they don't take a person's tolerance into account

2020;105:975e991977

Autoantibodies A key diagnostic criterion for all AIH scoring systems is the detection of autoantibodies [9, 139, 140], which not only assists in the diagnosis but also allows differentiation of AIH types (Table 2)

Diluting that into an adults ~3 litres of plasma changes the arithmetic considerably, but the point stands: the vial format was designed around commercial convenience, not around any dose that the mechanistic literature identified as biologically relevant