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Description

Autoimmune disorders are believed to have three phases ( Figure 1 )

Paget, S

Under intestinal inflammation, increased intestinal permeability allowed for bacterial translocation and passage from the portal vein into the liver, contributing to the pathogenesis of numerous diseases such as AIH and cholestatic liver disease

By functionalizing the nanocarrier with a protamine biopolymer and an MUC1-specific aptamer, the researchers achieved precise tumor targeting, leveraging the overexpression of MUC1 receptors on breast cancer cells