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Thus, whether NRF2 acts as a protector or a promoter of ferroptosis in IBD is influenced by factors such as cellular metabolism, microbial metabolites, and tissue-specific conditions

In contrast, Rab4 inhibited with 3-pyridinyl ethylidene hydroxyl phosphonocarboxylate (3-PEHPC) restores Drp1 function via the mTOR-independent pathway, reversing mitochondrial accumulation in lupus T cells ( Increased calcium flux also promotes oxidative stress-dependent T cell activation

High-dose vitamin C, vitamin D, and zinc are commonly included in these treatments, as they play crucial roles in supporting immune function and reducing inflammation

Genomic functional annotation reveals the vitamin B 6 biosynthetic pathway in GR-6 and GR-7 Comprehensive genomic analysis of Pediococcus acidilactici GR-6 and Lactobacillus fermentum GR-7, and along with the pathogen A