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Qiu J, Bosch MA, Zhang C, Rnnekleiv OK, Kelly MJ

In one study, supplementation with pycnogenol at 100 mg/day for eight weeks reduced venous leg edema by 40% (Belcaro 2015)

We did not adjust this model for data that did not meet tests for normality, as mixed linear models are generally robust to violations of this assumption (Knief and Forstmeier, 2021)