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We characterized that I-TDMs not only enhanced the surface expression of CD163 and CD206 but also increased arginase and decreased iNOS protein expression

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On the other hand, high levels of oxoproline were found in fibroblasts, MSC, and keratinocytes undergoing replicative senescence, pointing to an increase in GSH degradation (Quijano et al., 2012

The cryo-EM density maps are available in the Electron Microscopy Data Bank with accession codes EMD-69144 (apo), EMD-69143 (substrate and ADPVO 4 -bound) and EMD-69145 (ATP-bound)