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Ethics statement The animal study was reviewed and approved by Institutional Bioethics and Biosecurity Committee of the Instituto de Investigaciones Qumico-Biolgicas, Universidad Michoacana de San Nicols de Hidalgo

Excessive excitation can promote anxiety-like behavior because of increased excitatory transmission or decreased inhibitory transmission, and its imbalance leads to the disorder of amygdala neural circuit (Wu et al., 2008)