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However, mild acute toxicity and suboptimal therapeutic efficacy have been observed following the administration of viral vectors, likely due to off-target transduction of liver-resident antigen-presenting cells (APCs), such as Kupffer cells and hepatic stellate cells [304, 305]

Efficacy of cryotherapy associated with laser therapy for decreasing severity of melphalan-induced oral mucositis during hematological stem-cell transplantation: a prospective clinical study

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These research investments will help clarify whether OSCs can deliver on their promise as sustainable, dual-action therapeuticsor whether their use necessitates the same cycle of vigilance required for conventional antibiotics