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PMID: 36730125 ACS Nano Presentation and Delivery of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand via Elongated Plant Viral Nanoparticle Enhances Antitumor Efficacy

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There is also a decline in the IgM memory compartment with age [361], which may contribute to a weakened immune response to polysaccharide antigens, increasing susceptibility to bacterial infections like pneumococcal disease [362,363,364]