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10.1038/sj.ijo.0801740

The pre- and post-GBCA images used to derive the CBV maps shared identical imaging settings, which help reduce the inter and intrasubject variability between the non-contrast T1W pre-GBCA image and the quantitative GBCA enhancement and benefit the training of our model

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Complementary approaches may include: Behavioral therapy or weight management counseling Sleep optimization (79 hours nightly) Stress management techniques Evaluation and treatment of coexisting conditions (insulin resistance, sleep apnea, depression) FDA-approved oral weight loss medications (orlistat, phentermine/topiramate ER, naltrexone/bupropion) as alternatives to injectables (note: phentermine monotherapy is approved for short-term use only) Patients should maintain realistic expectationsweight loss may be slower with hypothyroidism, even when well-controlled