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Description

In insulin resistant states there is an increase in lipolysis in adipose depots and inhibition of FFA uptake, increasing FFA delivery to the liver

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Hypoxia in renal tubular cells can cause tubular cell expansion, degeneration, apoptosis and cytokine production and secretion, thereby activating interstitial fibroblasts, increasing extracellular matrix production and promoting the progression of tubulointerstitial fibrosis (40)

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Aging (Albany NY) 13 (22), 2451124523

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NMR Biomed 5(2):5964

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