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The referred aggregates promote microglial activation, which surprisingly appears to play a dual role in disease pathophysiology (280)

Product labeling must include 35 Product name The term dietary supplement or similar term (i.e., herbal supplement) Name and location of the manufacturer, along with a domestic address and phone number for reporting serious adverse events Nutrition labeling in the form of a Supplement Facts panel with the following information (see Figure 1 ): Serving size Number of servings per container Listing of each dietary ingredient in the product Amount of dietary ingredient per serving (Exception: ingredients in a proprietary blend) Amount per serving listed as a quantitative amount by weight, as a percentage of the Daily Value, or as both A list of other ingredients not declared on the Supplement Facts label (usually excipients such as preservatives or dyes) Net quantity of contents Figure 1

Xie J, Reverdatto S, Frolov A, Hoffmann R, Burz DS, Shekhtman A (2008) Structural basis for pattern recognition by the receptor for advanced glycation end products (RAGE)