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It increased the number of TH-positive cells in the substantia nigra and the density of TH positive neurofibers in the striatum

Tissue heterogeneity, MRS voxel size, lesion volume and localization may affect the local concentration of selective metabolites: normal tissue as far as perifocal oedema, non-viable parts of the tumour, calcifications, cysts, haemorrhage in the voxel and close bone structures may produce artifacts and misleading results

This includes older adults, those with diagnosed deficiencies, individuals with gastrointestinal disorders, or those on specific medications that affect B12 absorption

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