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The silymarin standard group displayed no histopathological alterations in most liver sections, with only a few binucleations of hepatocytes observed in some areas (Figures 11E, F), and apparent normal renal parenchyma, although some renal tubules exhibited mild vacuolar degeneration (Figures 12E, F)

These studies indicate that 5-amino-1mq can delay skin fibroblast senescence by regulating NAD+ metabolism, providing a novel intervention target for skin anti-aging research

The theory is that by increasing antioxidant levels, the body can better protect melanocytes from the oxidative damage that leads to depigmentation

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