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GPX3 and Cardiovascular Diseases (CVDs) CVDs, including ischemic heart disease, stroke, heart failure, peripheral arterial disease, and other cardiac and vascular conditions, are the primary cause of mortality worldwide and significantly impair quality of life [60]

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In addition, the molecular perturbations induced in HPV-16 E7 Mut did not interfere with the ability of the oncoprotein to bind in vitro to the oncosuppressor protein pRb, a molecular target of E7 (Figure 4C)