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Moreover, change in cellular localization and secretion of ARSs in cancer cell exert unique activities during the development of cancers, such as YRS in gastric cancer (Wei et al., 2014), and KRS in colon cancer (Nam et al., 2018)

10.1074/jbc.R116.735894 [DOI] [PMC free article] [PubMed] [Google Scholar] Carlisle DB (1958)

The developers, uniQure, hope to gather enough evidence from the ongoing trial to pursue FDA approval without a full Phase 3 trial, but more data is still needed

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