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However, with the prevalence of skin permeation enhancement methods (such as microneedles and laser) used in cosmetic and pharmaceutical industry 15 , copper compounds may pose a higher risk to cause skin irritation, which necessitates a thorough skin toxicity testing

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This combination of higher achievable plasma levels and better tolerability explains why vitamin C is a core ingredient in immune, recovery, and skinfocused IV drips

doi: 10.3389/fendo.2023.1226687 Received 22 May 2023 Accepted 01 August 2023 Published 16 August 2023 Volume 14 - 2023 Edited by Iveta Yotova, Medical University of Vienna, Austria Reviewed by Michele Da Broi, University of Sao Paulo, Brazil