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In further embodiments, the invention encompasses a method of providing muscular therapy by contacting a cell expressing NNMT with one or more cations of the invention and with one or more cations chosen from Tables 3a and 3b

The resulting BsNb-ncAA demonstrated high affinity, stability, and specificity

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Once in circulation, apigenin binds serum transferrin and distributes to the liver, kidney, and intestines (109)