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Future research should develop more efficient multi-omics data integration methods, enhancing the interpretability and clinical applicability of AI algorithms that will optimize precision medicine and personalized nursing in resource-limited areas, and establishing interdisciplinary collaboration platforms to promote the translation of basic research into clinical practice

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In addition, it improves arterial stiffness and immune function, and reduces inflammatory markers responsible for systemic inflammation [151]

162 In this discussion, we focus on lactate, pyruvate, alpha-ketoglutarate, and ketone bodies, which are frequently reported in the context of cancer cachexia