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Genetic mutations (e.g., SLC6A1 and SHANK3) have pleiotropic effects on the E/I balance, complicating target selection [112]

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A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, Nrf2, and epigenomics

For example, researchers have complied genomics, metabolomics, proteomics, and microbiome analyses in a single framework to develop individualized dietary interventions for T2D ( FADS1 and FADS2 genes ( Major upstream causal factor is the genome, with metabolome, microbiome and other omics being mediators which are impacted by age, gender, demographic characteristics, and pharmacological intervention ( Integration of omics involves collection of data from various sources, i.e., biological structure (cell, organ, tissue), samples (urine, blood), conditions (time-points, experimental groups) etc