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doi: 10.1038/s41598-020-76562-9 153 Meja-GranadosDMVillasana-SalazarBLozano-GarcaLCavalheiroEAStrianoP

Glutamine, a copious nonessential amino acid in the cellular environment, plays a fundamental role in diverse biological processes, including protein synthesis, immune modulation and cellular metabolism (138)

10.1016/0024-3205(86)90540-0 Hoshi T, Heinemann S: Regulation of cell function by methionine oxidation and reduction

This process yields a 3 kDa soluble peptide, p3, on the lumenal side, and the APP intracellular domain (AICD) peptide on the cytoplasmic side (Haass et al, 1993)