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SAMe is also important for encouraging a normal, healthy inflammatory response

It can support skin health and hair quality by providing antioxidants, vitamins, and minerals involved in tissue repair and collagen support

One of the earliest and most damaging events is excitotoxicity, where oxygen and glucose deprivation lead to excessive release of glutamate and over-activation of NMDA and AMPA receptors, causing calcium influx and neuronal hyperexcitation (25)