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doi: 10.1016/j.leukres.2015.12.008 12 McBrayerSKChengJCSinghalSKrettNLRosenSTShanmugamM

In 2001, the role of Rho GTPases in aqueous humor outflow was initially proposed due to their presence in the trabecular meshwork, where they could induce calcium sensitization, leading to smooth muscle contraction in rabbit eyes [270,271]