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MSCs, for instance, have the ability to release substances that prevent ferroptosis, shielding lung cells from iron-dependent lipid peroxidation (89)

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Figure 3 Commensal luminal bacteria inhibit the colonization of pathogens by, for example, the production of bacteriocins, pH modification of the luminal content, and competition for nutrients required for the growth of pathogens (Bharadia et al., 2020)

Furthermore, elevated ROS levels promote the formation of the necrosome, a complex comprising receptor-interacting protein kinase 1 (RIP1) and RIP3 kinases that phosphorylate mixed lineage kinase domain-like (MLKL) proteins, leading to cell membrane destruction and the release of cellular contents, ultimately resulting in cell necrosis (Wu et al., 2020