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Additionally, a negative correlation between complex II activity and oxidative stress measures has been reported in BD patients during depressive episodes, suggesting that mitochondrial oxidative stress related mitochondrial dysfunction may contribute to bipolar depression [50]

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Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y et al (2022) Cepharanthine attenuates early brain injury after subarachnoid hemorrhage in mice via inhibiting 15-lipoxygenase-1-mediated microglia and endothelial cell ferroptosis