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In lung metastatic niches with low TGF-2 levels, DTCs dormant state is more readily disrupted, leading to outgrowth

To examine the role of ASGPR in efficacy of various liposome formulations, wildtype and ASGPR knockout mice were administered MC3 liposomes containing the AD-1661 siRNA composition, at 3, 1, and 0.3 mg/kg as described in Example 1

Bergknut N, Smolders LA, Grinwis GC, Hagman R, Lagerstedt AS, Hazewinkel HA, Tryfonidou MA, Meij BP: Intervertebral disc degeneration in the dog

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