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Medina-MorenoSZapataJCCottrellMLLeNMTaoSBryantJet al

Preclinical and observational data available for the individual components

In a mouse model of multiple sclerosis, BHB can activate the Notch signaling pathway, improve stem cell homeostasis, and promote the survival and regeneration of neurons

Cyanogenic glycosidessuch as linamarin, linustatin, neolinustatin, lotaustralin, and amygdalinare nitrogenous metabolites that can be converted by intestinal -glycosidase into cyanohydrin, which breaks down into hydrogen cyanide